Participated in developing five clinical candidates
Out-licensed two projects for pharmaceutical companies
Inventors in
13 patents
Published >100 research papers
We are here to help your molecular discovery!
How can we help you?
We provide services tailored to your needs, from target validation to lead optimization, helping to accelerate your drug discovery process. Here are some examples of how we can help you:
If you have a novel drug discovery target
Using Aurlide’s proprietary technology for vHTS, the hit rate for identifying the first-in-class molecule is very high. Thus far, our team has identified first-in-class molecules for nearly 20 target proteins.
If you have some hits
Using our in-house technology, we can incorporate your existing hits and inactive molecules into our vHTS model, which again provides both new types of structural solutions to your hit space, and we can enlarge all hits to a series of compounds.
Using Aurlide’s technology for hit space expansion, the hit-to-lead optimization is practically done, and the optimization of hit molecules, including core hopping, to novel high-affinity ligands can be applied quickly, thus saving both time and money in progress to clinical phases.
If you want to turn your hits to lead molecules
The hit-to-lead process can be quickly applied with the seamless collaboration between our experts and your medicinal chemistry team.
How about animal testing?
Simultaneous optimization of binding into proteins from human and other wished species. By using Aurlide’s discovery platform, it is possible to optimize molecules to bind both to protein in the intended target species and species used in animal tests. This way, we can significantly lower the risk for failures at the pre-clinical phase.
If you need to understand the binding site and binding mode of your molecule
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